ABSTRACT The effect growing media and concentration of the plant growth regulator Dekamon to growth and yield of melon (Cucumis melo L). The aim of this research is find out best kind effect of growing media and concentration of the plant growth regulator Dekamon and interaction both of two treatment on growth and yield of melon. This research was conducted at the Balai Pengkajian Teknologi Pertanian (BPTP) Banda Aceh at May until August 2013. This research used Randomized Completely Block Design 3 x 5 with 2 factors and 3 replications. First factor is kind of growing media with 3 levels; soil, soil + husk, and soil + compost. The second factor is concentration of the plant growth regulator Dekamon with 4 levels; control (0 ml L-1), 0,15 ml L-1, 0,20 ml L-1, 0,25 ml L-1, dan 0,30 ml L-1. Observations parameter of inspected is; height of plant (cm), diameter rods (cm), number of leafes per plant (blade), number of fruit weight per plant (g) and number of diameter fruit per plant (cm). Results of this experiment shows that the growing media give significant effect on height of plant at the age 36 dap and diameter rods 16 dap, no significant on height of plant (at the age 6, 16, and 26 dap), diameter rods (at the age 6, 26 and 36 dap), number of leafes per plant (at the age 6, 16, 26 and 36 dap), number of fruit weight per plant and number of diameter fruit per plant at the age 70 dap. Growing media of soil + husk (M2) is better growing media to height of plant and diameter rods but soil + compost(M3) is better to give generative result of melon. The concentration of the plant growth regulator Dekamon give highly significant effect to diameter rods at the age 26 dap, significant effect on height of plant at the age 26 dap and number of leafes 16 dap, and no significant on height of plant (at the age 6, 16, and 36 dap), diameter rods (at the age 6, 16 and 36 dap), number of leafes per plant (at the age 6, 26 and 36 dap), number of fruit weight per plant and number of diameter fruit per plant at the age 70 dap. At concentration of 0,20 ml L-1 (K2) give better results to on height of plant, diameter rods and number of leafes per plant but concentration of 0,30 ml L -1 (K4) is better to give generative result of melon. Research also show there is no influence significantly of interaction between The effect growing media and concentration of the plant growth regulator Dekamon on all variables observed. keywords : Cucumis melo L, growing media, plant growth regulator Dekamon 22,43 L.