The aims of this research was to evaluate the effect of papain and bromelain enzymes in feed on growth and feed utilization in post larvae Litopenaeus vannamei shrimp. The research was conducted for 42 days at the Fish Hatchery Laboratory, Faculty of Marine Affairs and Fisheries, Syiah Kuala University. The completely randomized design consisting of four treatments and three replications were used in this study. The tested treatment was; experimental feed without enzyme, experimental feed + 1% papain enzyme, experimental feed + 1% bromelain enzyme, and experimental feed + 1% papain enzyme + 1% bromelain enzyme. The shrimp was fed the tested feed five times on 07.00 AM, 11.00 AM, 03.00 PM, 07.00 PM and 11.00 PM for 42 days. The ANOVA test results showed that the addition of papain and bromelain enzymes in the feed had a significant effect on weight gain, daily growth rate and specific growth rate of vaname shrimp (P0.05). The best treatment was found in treatment D (a combination between of 1% papain enzyme + 1% bromelain enzyme) with the weight gain of 1.15 g of vaname shrimp, daily growth rate of 0.027 g day-1, specific growth rate of 7.14% day-1, feed conversion ratio of 1.85, and feed efficiency 54.15%, but the highest survival was found at treatment A. It is concluded that the best treatment is a combination between of 1% papain enzyme + 1% bromelain enzyme. Key words: Litopenaeus vanname, papain enzyme and bromelain enzyme