ABSTRACT The purpose of this study was to determine the business risk, asset growth, profitability, and time interest earned simultaneously to the capital structure of the companies listed on the Indonesia Stock Exchange in 2009-2011. The number of elements in the study sample was 25 companies from 2009 to 2011 to obtain a 75-year observation data. The results obtained coefficients greatest effect on the capital structure of the company is manufacturing in IDX profitability. Business risk, asset growth, profitability, and time greatly affect the interest earned on the capital structure of manufacturing companies on the Stock Exchange reached 41.4 percent and the remaining 58.6 percent is influenced by other variables outside the model of this study. The test results using the t-test test showed that business risk, asset growth, profitability, and time interest earned partially significant effect on the capital structure on manufacturing companies on the Stock Exchange. Testing using the F-test tests showed that business risk, asset growth, profitability, and time interest earned simultaneously significant effect on the capital structure of manufacturing companies on the Stock Exchange. From the research, it turns out that the coefficient of the effect on the capital structure was variable profitability therefore the expected future profitability can be utilized with probably due to becoming one of the most influential factors to the increase in the dividend. Keywords: Capital Structure, Business Risk, Profitability, Time Interest Earned, and Asset Growth