PENGARUH MINYAK SAMIN DAN MINYAK KELAPA SAWIT TERHADAP KADAR KOLESTEROL HDL DARAH KELINCI JANTAN (Oryctolagus cuniculus) Lailan Kumala (NIM. 0802101010013) ABSTRAK Penelitian ini bertujuan untuk mengetahui kadar kolesterol HDL darah kelinci jantan (Oryctolagus cuniculus) yang diberi minyak samin dan minyak kelapa sawit. Hewan yang digunakan dalam penilitian ini adalah sembilan ekor kelinci jantan umur berkisar (5-6) bulan. Selama penelitian kelinci diberi makanan kangkung dan wortel serta diberi minum ad libitum. Rancangan yang digunakan adalah rancangan acak lengkap (RAL) pola searah dengan tiga kelompok perlakuan. Masing-masing kelompok perlakuan terdiri dari tiga ekor kelinci. Kelompok I sebagai kontrol diberi 2ml akuades/ekor/hari, kelompok II diberi 2 ml minyak samin/ekor/hari dan kelompok III diberi minyak kelapa sawit 2 ml/ekor/hari. Masing-masing kelompok diberi perlakuan selama 14 hari berturut-turut secara oral menggunakan sonde lambung. Hari berikutnya setelah selesai perlakuan sampel darah diambil melalui Vena auricularis sebanyak 2 ml. Kadar kolesterol HDL darah dianalisis dengan metode presipitat. Rata-rata (±SD) kadar kolesterol HDL (mg/dl) pada K I, K II, dan K III berturut-turut adalah 27,00±6,24; 41,33±9,24; 99,00±3,00. Hasil penelitian menunjukkan bahwa kadar kolesterol HDL darah kelinci yang diberi minyak kelapa sawit lebih tinggi dari kadar kolesterol HDL darah kelinci yang diberi minyak samin. The Effect of Samin Oil and Palm Oil on Blood HDL Cholesterol Level of Male Rabbit (Oryctolagus cuniculus) ABSTRACT The aim of this research was to find out the blood HDL cholesterol level of male rabbit (Oryctolagus cuniculus) by administration of samin oil and palm oil. Nine male rabbits at the age of (5-6) month. Were used in this study the rabbits were divided into three groups using ransomised complete design. All rabbits were fed (kangkung and carrot) and water ad libitum. Group I as control which was given 2 ml aquades/head/day, group II which was given 2 ml samin oil/head/day and group III which was given 2 ml palm oil/head/day. The treatment had been given directly by using the sonde bounce up for 14 day regularly. The day after, sample blood was presipitat method. Mean (±SD) of Rtae of cholesterol HDL (mg/dl) at group I, II, and III were 27.00±6.24; 41.33±9.24; 99.00±3.00, rspectively. The result showed that, the blood HDL cholesterol level of rabbit that giving palm oil higher than samin oil.