Penelitian ini bertujuan mengetahui pengaruh berbagai jenis arang aktif yang digunakan sebagai suplementasi aditif dalam pakan ikan kuwe (Caranx ignobilis), terhadap gambaran histologis lambung dan usus halus. Pelaksanaan penelitian di Balai Perikanan Budidaya Air Payau (BPBAP) Ujung Batee dan Laboratorium Mikroteknik Jurusan Biologi Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Syiah Kuala, pada bulan Maret hingga September 2018. Penelitian menggunakan Rancangan Acak Lengkap yang terdiri atas 5 perlakuan dan 4 ulangan diaplikasikan dalam penelitian ini. Perlakuannya adalah pemberian pakan dengan penambahan arang akif dari sumber yang berbeda, yakni; tempurung kelapa, kayu bakau, sekam padi, dan cangkang kelapa sawit. Konsentrasi arang aktif dalam formulasi pakan sebanyak 2%. Ikan diberi pakan perlakuan sebanyak dua kali sehari secara ad station selama 42 hari pemeliharaan. Ikan dibedah dan dibuat sediaan histologis dengan metode parafin. Tinggi dan lebar vili usus halus ikan kuwe diukur dan dianalisis dengan analisis varian, kemudian dilanjutkan dengan uji Duncan. Ukuran tinggi dan lebar foveola gastrica tertinggi terdapat pada perlakuan pakan dengan penambahan arang aktif sekam padi, tinggi vili usus paling tinggi terdapat pada perlakuan pakan dengan penambahan arang aktif kayu bakau, vili usus paling lebar terdapat pada perlakuan pakan tanpa penambahan arang aktif (kontrol). The aim of this research was to determine the effect of various types of activated charcoal that were used as supplementation additives in Caranx ignobilis feed to the histological picture of the stomach and small intestine. The research was conducted at Ujung Batee Brackishwater Aquaculture Center (BPBAP) and Microtechnic Laboratory of Biology Department, Faculty of Mathematics and Natural Sciences, Syiah Kuala University, from March to September 2018. Research was used Completely Randomized Design consisting of 5 treatments and 4 replications were applied in this reseach. The treatments tested were feeding with additions of a charcoal from different source, that is; coconut shell, mangrove wood, rice husk, and oil palm shells. The concentration of activated charcoal in the feed formulation was 2%. The fish were fed with treatment twice a day in ad-station for 42 days of maintenance. Fish were dissected and histological preparations were made using the paraffin method. The height and wide of villi of the small intestine of the fish were measured and analyzed by analysis of variance, then continued with the Duncan test. The highest height and width of foveola gastrica were found in the treatment of feed with additions of activated charcoal rice husk, the highest height of intestinal villi was found in the treatment of feed with additions of activated charcoal mangrove wood, the widest intestinal villi was found in feed treatment without additions of activated charcoal (control).