Abstrak Penelitian ini berjudul Komunikasi Interpersonal Relawan Lembaga Sosial Terhadap Keluarga Pasien Rumah Singgah Blood For Life Foundation Dalam Memberi Motivasi Hidup (Studi Pada Lembaga Sosial Blood For Life Foundation). Penelitian ini bertujuan untuk mengetahui komunikasi interpersonal relawan dalam memberi motivasi hidup kepada pasien Blood For Life Foundation. Penelitian ini menggunakan metode deskriptif kualitatif. Teknik pengumpulan data yang digunakan ialah wawancara pada lima informan dan melakukan observasi dan dokumentasi. Fokus penelitian ini adalah pada komunikasi interpersonal anggota relawan terhadap pasien, dikaji dari lima indikator efektivitas komunikasi interpersonal seperti keterbukaan, empati, sikap mendukung, sikap positif, dan kesetaraan. Teori yang digunakan ialah teori De Vito (Pendekatan Humanistik) yang mana teori ini memandang hubungan interpersonal sebagai sebuah sistem, yang terdiri dari komponen input, proses/pengolahan dan output. Teori ini menunjukkan bagaimana anggota BFLF Aceh memiliki sebuah harapan, keinginan agar pasien tetap bersemangat untuk sembuh, hal ini disebut sebagai input. Oleh sebab itu relawan BFLF melakukan interaksi interpersonal yang disebut dengan proses, dengan cara menyampaikan pesan yang dapat menumbuhkan semangat serta motivasi hidup pasien di rumah singgah. Agar terciptanya hubungan interpersonal yang efektif, relawan BFLF juga telah menerapkan dan memperhatikan lima komponen efektivitas komunikasi interpersonal seperti keterbukaan, empati, sikap mendukung, sikap positif dan kesetaraan. Hal itu mereka lakukan dalam kehidupan sehari-hari ketika sedang berkomunikasi interpersonal dengan pasien seperti kanker, meskipun mereka tidak memahami secara teori dan juga tidak memiliki pembekalan tentang komunikasi interpersonal pasien sebelumnya. Kata kunci : Komunikasi Interpersonal, Pasien, Keluarga, Motivasi Hidup ABSTRACT The study is entitled Interpersonal Communication Volunteer Social Institutions to Family Patient of Halfway House Blood For Life Foundation in Giving Life Motivation (Study At The Social Institute Blood For Life Foundation). The purpose of this research is to know the interpersonal communication of volunteer to the patient in giving life motivation in The Blood For Life Foundation. This study used descriptive qualitative method. The data collection techniques used were interviews with five informants and doing observation and documentation. The focus of this research is on interpersonal communication of volunteer members to patient, examined from five indicators of interpersonal communication effectiveness such as openness, emphaty, supportive attitude, positive attitude, and equality. The theory used is the theory of De Vito (Humanistic Approach) in which this theory views the interpersonal relationship as a system, which consists of input, process / processing, and output components. This theory shows how members of BFLF Aceh have a hope, the desire for the patient to remain eager to heal, this referred to as input. In order to create effective interpersonal relationships, BFLF volunteers have also applied and considered five components of the interpersonal communication effectiveness such as openness, empathy, supportive attitude, positive attitude, and equality. They do this in daily life while communicating interpersonally with patients such as cancer, although they do not understand theoretically and also have no briefing on the patient’s previous interpersonal communication. Keywords: Interpersonal Communication, Patient, Family, Commu ABSTRACT The study is entitled Interpersonal Communication Volunteer Social Institutions to Family Patient of Halfway House Blood For Life Foundation in Giving Life Motivation (Study At The Social Institute Blood For Life Foundation). The purpose of this research is to know the interpersonal communication of volunteer to the patient in giving life motivation in The Blood For Life Foundation. This study used descriptive qualitative method. The data collection techniques used were interviews with five informants and doing observation and documentation. The focus of this research is on interpersonal communication of volunteer members to patient, examined from five indicators of interpersonal communication effectiveness such as openness, emphaty, supportive attitude, positive attitude, and equality. The theory used is the theory of De Vito (Humanistic Approach) in which this theory views the interpersonal relationship as a system, which consists of input, process / processing, and output components. This theory shows how members of BFLF Aceh have a hope, the desire for the patient to remain eager to heal, this referred to as input. In order to create effective interpersonal relationships, BFLF volunteers have also applied and considered five components of the interpersonal communication effectiveness such as openness, empathy, supportive attitude, positive attitude, and equality. They do this in daily life while communicating interpersonally with patients such as cancer, although they do not understand theoretically and also have no briefing on the patient’s previous interpersonal communication. Keywords: Interpersonal Communication, Patient, Family, Communication.