HUBUNGAN ANTARA BEBERAPA PROFIL BIOKIMIA DARAH DENGAN VISKOSITAS MUKUS SERVIKS SAPI ACEH YANG MENGALAMI SINKRONISASI BIRAHI ABSTRAK Penelitian ini bertujuan mengetahui hubungan antara beberapa profil biokimia darah dengan viskositas mukus serviks sapi aceh yang mengalami sinkronisasi birahi. Dalam penelitian ini digunakan delapan ekor sapi aceh betina dengan kisaran umur 3-7 tahun dan memiliki bobot badan 150-250 kg, sudah pernah beranak dan memiliki dua kali siklus reguler. Seluruh sapi disinkronisasi menggunakan prostaglandin F2 alfa (PGF2α) dengan dosis 25 mg dengan pola campuran. Pengamatan birahi dilakukan selama 30 menit pada pagi (08.00 WIB) dan sore hari (16.00 WIB) setelah penyuntikan PGF2α terakhir. Sapi dianggap birahi apabila menunjukkan gejala seperti vulva bengkak dan merah, gelisah, nafsu makan menurun, dan keluarnya mukus serviks. Sampel mukus serviks dikoleksi dengan metode aspirasi dengan kateter steril dan disposible syringe 20 ml. Kateter dimasukkan ke dalam vagina melalui vulva yang diiringi dengan palpasi rektal untuk mengarahkan kateter masuk ke dalam serviks. Pengambilan sampel darah dilakukan pada sesaat setelah koleksi mukus serviks. Profil biokimia darah yang diukur adalah protein total, kolesterol total, dan glukosa menggunakan teknik spektrofotometri. Rata-rata (±SD) kadar protein total darah sapi aceh dengan mukus serviks encer; sedang; dan kental masing-masing adalah 8,2; 9,75±0,9; dan 9,48±1,1 g/dl. Rata-rata (±SD) kolesterol total darah sapi aceh dengan mukus serviks encer; sedang; dan kental masing-masing adalah 123,0; 146,0±2,8; dan 162,2±39,90 mg/dl. Rata-rata (±SD) kadar glukosa darah sapi aceh dengan mukus serviks encer; sedang; dan kental masing-masing adalah 39,0; 32,5±10,60; dan 38,8±18,24 mg/dl. Disimpulkan bahwa peningkatan kadar protein total dan kolesterol total cenderung meningkatkan viskositas mukus serviks sedangkan kadar glukosa cenderung tidak memengaruhi viskositas mukus serviks sapi aceh. THE RELATIONSHIP BETWEEN SEVERAL BLOOD BIOCHEMICAL PROFILES WITH THE VISCOSITY OF CERVICAL MUCOUS IN ESTROUS SYNCHRONIZED ACEH CATTLE ABSTRACT The aim of this study was to determine the relationship between several blood biochemical profiles with the viscosity of cervical mucus in estrous synchronized aceh cattle. This study used eight female aceh cattle with range of age 3-7 years and have a body weight of 150-250 kg, had been given birth and has two regular cycles. All cattles were synchronized using prostaglandin F2 alpha (PGF2α) at a dose of 25 mg with mixed pattern. Observation of estrous was done for 30 minutes in the morning (08.00 WIB) and afternoon (16.00 WIB) after the last PGF2α injection. Cattle are considered estrous when showing symptoms such as swollen and red vulva, anxiety, decreased appetite, and cervical mucus discharge. Cervical mucus samples were collected by aspiration method with sterile catheter and 20 ml disposible syringe. The catheter was inserted into the vagina through the vulva accompanied by rectal palpation to direct the catheter into the cervix. Blood sampling was performed immediately after the collection of cervical mucus. The blood biochemical profile measured was total protein, total cholesterol, and glucose using spectrophotometry techniques. Average (±SD) total protein content of cow blood of aceh with dilute cervical mucus; medium; and the thickness of each is 8.2; 9.75±0.9; and 9.48±1.1 g/dl. Average (±SD) total cholesterol of cow blood of aceh with dilute cervical mucus; medium; and the thickness of each is 123.0; 146,0±2.8; and 162.2±39.90 mg/dl. Average (±SD) blood glucose levels of aceh cows with dilute cervical mucus; medium; and condensed are 39.0 respectively; 32,5±10,60; and 38.8±18.24 mg/dl. It was concluded that elevated level of total protein and total cholesterol tended to increase the viscosity of the cervical mucus while glucose levels tended not to affect the viscosity of cervical mucus of aceh cattle.