ABSTRAK Telah dilakukan sintesis dan karakterisasi senyawa kompleks Zink(II) dengan ligan senyawa flavonoid dari tanaman pala (Myristica fragrans Houtt). Objek utama penelitian ini adalah mendapatkan senyawa flavonoid jenis dihydrocaemferol dari ekstrak etil asetat akar pala. Isolasi senyawa telah dilakukan dengan kromatografi kolom gravitasi. Setelah dilakukan beberapa uji, ekstrak etil asetat akar tanaman pala mengandung senyawa flavonoid jenis dihydrocaemferol. Sintesis kompleks dihydrocaemferol dengan ZnSO4.7H2O dilakukan dalam pelarut metanol dengan perbandingan mol ligan dan logam 1:1,1. Spektrum FT-IR menunjukkan bahwa kompleks telah diperoleh. Pergeseran bilangan FT-IR C=O 1637,548 cm-1 menjadi 1638,184 cm-1 dan O-H 3356,915 cm-1 menjadi 3335,889 cm-1 mengindikasikan bahwa senyawa kompleks telah didapatkan. Kata Kunci : Sintesis, dihydrocaemferol, senyawa kompleks, tanaman pala (Myristica fragrans Houtt), flavonoid. ABSTRACT Synthesis of complex compound of zinc(II) with compound of flavonoid as ligand has been carried out. The objective of this study is to obtain flavonoid compounds of dihydrocaemferol type from ethyl acetate extract of nutmeg root. Isolation of the compound has been done by employing chromatography of grafitation coloumn. According to some tests, the extract of the nutmeg root contains the compound of flavonoid, namely dihydrocaemferol. Complex synthesis of dihydrocaemferol and ZnSO4.7H2O has been carried out in methanol solution with mole ratio of ligand and metal of 1:1,1. FT-IR spectrum shows that the complex has been obtained. The shifting wavelength of FT-IR of C=O 1637,548 cm-1 to 1638,184 cm-1 and O-H 3356,915 cm-1 to 3335,889 cm-1 confirms that complex compound has been obtained. Keyword : Synthesis, dihydrocaemferol, complex compounds, nutmeg (Myristica fragrans Houtt), flavonoid