ABSTRACT Until recently sexually transmitted infections is still a problem in the field of health, social and economic development in various countries. In some countries stated that the provision of an intensive counseling program would reduce the prevalence of sexually transmitted infections. However, in most of the incidence of sexually transmitted infections are still relatively high. Most people with sexually transmitted infections are teens ages 15-29 years, but there are also cases in infants in because of her mother contracted while in the womb or at birth. High incidence of sexually transmitted infections, especially in the adolescent age group one of the main causes is the knowledge level of adolescents who are still relatively low, this will ultimately affect adolescent attitudes towards sexually transmitted infections. This study is a descriptive study, which aim to obtain information on knowledge and attitudes of adolescents in MAN Model Banda Aceh against sexually transmitted infections with the approach used is the cross sectional study. The population in this study includes all students in MAN Model Banda Aceh. While the number of samples taken for this study were 90 people, which was taken by stratified random sampling technique. The samples were then distributed proportionally based on grade level. The data was collected using a questionnaire and a descriptive analysis. Test results of students' level of knowledge and attitudes in MAN Model Banda Aceh to get a sexually transmitted infection in the majority of the students' knowledge in MAN Model in Banda Aceh that is equal to either category (75.6%), as well as to the attitude of the gain is still arriving in either category that is equal to (77.8%). Key words: Knowledge, Attitudes, Adolescent, Sexually Transmitted Infections