ABSTRAK Nama : Pratiwi Bunjamin Program Studi : Kedokteran Gigi Judul : Perbandingan Koloni Candida sp. dari Kultur Volume Kumuran Pemakai Gigi Tiruan Sebagian Lepasan Resin Akrilik Heat-Cured dan Self-Cured Candida merupakan mikroflora normal yang banyak didapatkan pada subjek pemakai gigi tiruan dibandingkan non-pemakai gigi tiruan. Gigi tiruan sebagian lepasan umumnya dibuat dari resin akrilik heat-cured dan self-cured. Penelitian ini bertujuan untuk melihat perbandingan koloni Candida sp. dari kultur volume kumuran pemakai gigi tiruan sebagian lepasan resin akrilik heat-cured dan self-cured. Penelitian ini dilakukan di Laboratorium Mikrobiologi FKH Unsyiah. Ini merupakan penelitian analitik dengan desain penelitian eksperimental. Subjek diperoleh dengan teknik purposive sampling dan bersedia mengisi informed consent. Volume kumuran 6 orang pemakai gigi tiruan sebagian lepasan resin akrilik heat-cured dan self-cured diinokulasikan ke SDA dan diinkubasi pada suhu 37oC selama 24-48 jam. Koloni Candida sp. dihitung dengan colony counter. Hanya 4 dari 6 sampel ( presisi 45% ) menunjukkan pertumbuhan koloni Candida sp. Namun analisis uji T menunjukkan koloni Candida sp. tidak ada perbedaan yang signifikan antara pemakai gigi tiruan sebagian lepasan resin akrilik heat-cured dan self-cured (p > 0,05). Disimpulkan bahwa tidak ada perbedaan jumlah koloni Candida sp. pada pemakai gigi tiruan sebagian lepasan resin akrilik heat-cured dibandingkan self-cured. Kata Kunci: Candida sp., heat-cured, self-cured, gigi tiruan sebagian lepasan resin akrilik. ABSTRACT Name : Pratiwi Bunjamin Departement : Dentistry Title : The Ratio of Candida sp. Colonies from Oral Rinse Volume Culture of Heat-Cured and Self-Cured Acrylic Resin Removable Partial Denture Wearer Candida as normal microflora in denture wearer was most founded than non-denture wearer. Removable partial denture is commonly made from heat-cured and self-cured acrylic resin. The objective of this study is to analyze the ratio of Candida sp. colonies from oral rinse volume culture of heat-cured and self-cured acrylic resin removable partial denture. This research was made in microbiology laboratory of Unsyiah Veterinary Faculty. This was an analytic research with experimental research design. The subjects were obtained with purposive sampling technique and agreed to fill informed consent. Oral rinse volume of 6 heat-cured and self-cured acrylic resin removable partial denture wearer were inoculated on SDA and incubated at 37oC for 24-48 hours. Candida sp. colonies were calculated with colony counter. Only 4 of 6 samples ( presition 45% ) showed the growth of Candida sp. colonies. However T Test analysis revealed that there was no significant difference in Candida sp. colonies between heat-cured and self-cured acrylic resin removable partial denture wearer (p > 0,05). It can be concluded that there is no difference in the number of Candida sp. colonies between heat-cured and self-cured acrylic resin removable partial denture wearer. Keywords : Candida sp., heat-cured, self-cured, acrylic resin removable partial denture.