Abstrak

Baca Juga : PENGARUH EKSTRAK ETANOL DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA) DALAM MENGHAMBAT PERTUMBUHAN METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS ISOLAT DARI INFEKSI NASOKOMIAL (DIANA AYUNI, 2015) ,

Baca Juga : UJI DAYA HAMBAT EKSTRAK ETANOL DAUN SISIK NAGA (DRYMOGLOSSUM PILOSELLOIDES (L) PRESL) TERHADAP PERTUMBUHAN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (SARI YANTI, 2014) ,

asi 12,5%, 25%, 50% dan 75%. kelompok kontrol positif yang digunakan adalah vancomycin 30 µg dan kelompok kontrol negatif yang digunakan adalah cmc 1%. hasil analisis data dengan menggunakan analysis of variance (anova) pada taraf 0,05 dan dilanjutkan dengan uji beda nyata terkecil (bnt). hasil penelitian meunjukkan bahwa ekstrak etanol daun ubi kayu (manihot esculenta crantz) varietas mentega pada konsentrasi diatas terhadap pertumbuhan bakteri mrsa dengan diameter zona hambat rata-rata masing-masing berturut adalah 12 mm, 10 mm, 11 mm, 14 mm. hasil analisa data menunjukkan adanya pengaruh yang sangat nyata (p< 0,05) dari hasil pemberian ekstrak daun ubi kayu dalam menghambat pertumbuhan methicillin resistant staphylococcus aureus. kesimpulan dari penelitian ini adalah ekstrak etanol daun ubi kayu (manihot esculenta crantz) varietas mentega memiliki efek antibakteri terhadap mrsa secara in vitro. kata kunci : ekstrak daun ubi kayu, antibakteri, methicillin resistant staphylococcus aureus. abstract methicillin- resistant staphylococcus aureus (mrsa) is a specific strain of staphylococcus aureus resistant to methicillin and penicillin group of antibiotics. therefore, alternative treatments need to be developed as a solution to overcome the problem of antibiotic resistance. one of the plants that have been used traditionally are the leaves of cassava (manihot esculenta crantz) butter varieties. this study aims to prove the antibacterial effect of ethanol extract of leaves of cassava (manihot esculenta crantz) varieties of butter against mrsa in vitro. this antibacterial inhibition test using the disc diffusion method. this study used a completely randomized design consisting of 4 treatment groups, one positive control group and 1 negative control group. the treatment group consisted of ethanol extract of leaves of cassava (manihot esculenta crantz) varieties butter concentration of 12.5 %, 25 %, 50 % and 75 %. positive control group used was 30 mg vancomycin and negative control group used is 1 % cmc. the results of the data analysis by using analysis of variance (anova) at the level of 0.05 , followed by least significant difference test (bnt). the results of the study reveals that the ethanol extract of leaves of cassava (manihot esculenta crantz) varieties of butter at a concentration above the mrsa bacterial growth inhibition zone diameter average of each row is 12 mm, 10 mm, 11 mm, 14 mm . the results of the data analysis showed a highly significant effect (p < 0.05) from the results of cassava leaf extract in inhibiting the growth of methicillin- resistant staphylococcus aureus. the conclusion of this study is the ethanol extract of leaves of cassava (manihot esculenta crantz) varieties butter has an antibacterial effect against mrsa in vitro. keywords : extract of leaves of cassava, antibacterial, methicillin-resistant staphylococcus

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