Abstrak

Baca Juga : PROFIL DARAH TIKUS PUTIH (RATTUS NORVEGICUS) YANG DIINFEKSIKAN TRYPANOSOMA EVANSI (Hasri Afandi, 2017) ,

Baca Juga : PENURUNAN JUMLAH SEL LEYDIG DAN SEL SERTOLI TIKUS PUTIH (RATTUS NORVEGICUS) STRAIN WISTAR SETELAH PEMBERIAN FORMALIN (MELIA SESVA DINA, 2017) ,

h diambil melalui sinus orbitalis menggunakan pipet kapiler. hasil analisis statistik menunjukkan rata-rata (±sd) kadar hemoglobin (g/dl) k0 12,00 ±0,72, k1 9,63 ±1,67, k2 9,83 ±1,30, dan k3 9,76 ±1,41. rata-rata (±sd) jumlah eritrosit (106/mm3) k0 7,06 ±0,78, k1 5,31 ±1,46, k2 5,35 ±0,97, dan k3 4,98 ±0,59. hasil uji anova menunjukkan kelompok k0 berpengaruh nyata (p0,05) antara kelompok perlakuan. disimpulkan bahwa pemberian formalin secara intraperitoneal dapat menurunkan kadar hemoglobin dan jumlah eritrosit tikus putih strain wistar. haemoglobin levels and number of erythrocyte in rats (rattus norvegicus) wistar strain after formalin administration abstract the aim of this study was to determine the effect of formalin administration via intraperitoneal to haemoglobin levels and to determine the number of erythrocyte in rats (rattus norvegicus) wistar strain. a number of 24 male rat used in this study. the research was design ed by uring completely randomized design (crd) with 4 unidirectional treatment groups. each group consisted of six rats. group control rat was given no treatment in the control group. formalin was administened by dosage of 1 mg/kg of body weight in the first group, 2,5 mg/kg of bw in second group, and 5 mg/kg of bw in the third group. each group was given the specific treatment for 14 days intraperitoneally. during the study, rat were fed as adlibitum. on day 15, blood was taken through orbital sinus by using a pipette capillary. the statistical analysis showed that mean (±sd) levels of haemoglobin (g/dl) were k0 12,00 ±0,72, k1 9,63 ±1,67, k2 9,83 ±1,30, and k3 9,76 ±1,4. mean (±sd) number of erythrocyte (106/mm3) were k0 7,06 ±0,78, k1 5,31 ±1,46, k2 5,35 ±0,97, and k3 4,98 ±0,59. the results of anova showed highly significant k0 (p0,05). it was concluded that the administration of formalin intraperitoneal can decrease haemoglobin levels erythrocyte in wistar strain

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