Abstrak

Baca Juga : EFEK ANTIBAKTERI EKSTRAK DAUN MAHKOTA DEWA(PHALERIA MACROCARPA (SCHEFF) BOERL) TERHADAP PERTUMBUHAN ENTEROCOCCUS FAECALIS (MUHAMMAD FAISAL ARIF HARAHAP, 2016) ,

Baca Juga : PENGARUH EKSTRAK DAGING BUAH MAHKOTA DEWA (PHALERIA MACROCARPA (SCHEFF) BOERL.) TERHADAP PERTUMBUHAN ENTEROCOCCUS FAECALIS (dian novita, 2015) ,

. data yang diperoleh pada pretest dan posttest dianalisis menggunakan uji anova dan didapatkan adanya perbedaan nyata (p < 0,05) antar kelompok perlakuan. data dianalisis menggunakan uji lanjutan lsd dan didapatkan adanya perbedaan nyata (p < 0,05) antara kelompok kn dengan kp, p1, p2 dan p3 namun tidak ada perbedaan yang nyata (p > 0,05) pada kelompok kp dengan p1, p2 dan p3. kesimpulan penelitian ini adalah pemberian ekstrak etanol daging buah mahkota dewa dapat menurunkan kadar gula darah tikus putih strain wistar yang diinduksi dengan alloksan. kata kunci: phaleria macrocarpa (sheff) boerl.), rattus norvegicus, diabetes mellitus. abstract ethanol extract of mahkota dewa’s flesh (phaleria macrocarpa (sheff) boerl.) was presumed to have hypoglycemia effect because it contains flavonoid, alkaloid, saponin, tannin, fenol, and steroid/triterpenoid. the study is aimed to understand the antihyperglicemic activity ethanol extract of mahkota dewa’s flesh in alloxan-induced wistar rats. this study was experimental study with pretest posttest with control group design using 30 male wistar rats that divided into 5 groups randomly. kn group (negative control) has been given aquadest; kp (positive control) has been given sitagliptin with a dose 1,8 mg/200 gbb; p1, p2 and p3 have been given extract of mahkota dewa with a dose of 110 mg/200 gbb; 220 mg/200 gbb; and 330 mg/200 gbb. the blood sugar level has been measured which is pretest on the 15th day of this study and posttest is on 21st day of this study. the data has been analyzed using anova and show that there is a significant difference (p < 0,05) on treatment group. the results of data analysis using lsd show that there is a significant difference (p 0.05) of blood sugar levels between the positive control group and the group with the mahkota dewa extract with a dose of 110 mg/200 gbb, 220 mg/200 gbb and 330 mg/200 gbb. the conclusion of this study is that the mahkota dewa’s flesh ethanol extract can decrease the level of blood sugar in the alloxan-induced wistar rats. keyword: phaleria macrocarpa (sheff) boerl.), rattus norvegicus, diabetes

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