Abstrak

Baca Juga : AKTIVITAS ANTIMIKROBIAL EKSTRAK ETIL ASETAT DAUN GALINGGANG (CASSIA ALATA) (Leyna Miska, 2016) ,

Baca Juga : ISOLASI DAN KARAKTERISASI SENYAWA AKTIF ANTIBAKTERI EKSTRAK ETIL ASETAT DAUN GALINGGANG (CASSIA ALATA) (Asmaul Husna, 2016) ,

f dengan konsentrasi 20% zona hambat yang dihasilkan sebesar 10 mm. ekstrak kasar etil asetat daun c. alata tidak aktif terhadap bakteri e.coli dan jamur c. albicans. berdasarkan hasil uji fitokimia, fraksi f memiliki kandungan metabolit sekunder golongan fenol yang menyumbang keaktifan dalam menghambat bakteri s. aureus. kata kunci: galinggang, cassia alata, antimikrobial, metabolit sekunder, ekstrak etil asetat, staphylococcus aureus, eschericia coli, candida albicans abstract extract ethyl acetate antimicrobial compound activity test of galinggang leave (cassia alata) has been carried out. this research to aim blocked ability of c. alata leave that growed in aceh toward growth of s. aureus, e. coli bacteria and c. albicans fungus. c. alata leave prepared then separated its compound using vacuum liquid chromatography that produced 6 group fraction, a (3,61 gram); b (2,02 gram); c (0,64 gram); d (0,92 gram); e (1,44 gram) and f (1,02 gram). antimicrobial activity test of crude extract and fractions toward s. aureus, e. coli bacteria and c. albicans fungus using agar diffusion method with 5%; 10% and 20% concentration. antimicrobial activity test result showed that an active ethyl acetate crude extract toward s. aureus bacteria on 5%; 10% and 20% concentration with blocked zone 7,5 mm; 8,5 mm and 10 mm respectively. the most active fraction toward s. aureus bacteria is f fraction on 20% concentration produced blocked zone among 10 mm. ethyl acetate crude of c. alata leave in active toward e. coli bacteria and c. albicans fungus. based on phytochemical test result, f fraction has secondary metabolite from fenol group that estimated active to blocked s. aureus bacteria. keyword: galinggang, cassia alata, antimicrobial, secondary metabolite, ethyl acetate extract, sthaphylococcus aureus, eschericia coli, candida

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