Abstrak

Baca Juga : FORMULASI SEDIAAN KRIM EKSTRAK ETANOL PLIEK U SERTA UJI AKTIVITASNYA TERHADAP ISOLAT KLINIS STAPHYLOCOCCUS AUREUS (Citra Nabilla, 2018) ,

Baca Juga : FORMULASI SEDIAAN SALEP EKSTRAK ETANOL RESIDU HEKSAN PLIEK U SERTA UJI AKTIVITAS ANTIBAKTERI TERHADAP STAPHYLOCOCCUS AUREUS (WILFA HUSNA, 2019) ,

ubahan organoleptik dan homogenitas sedangkan daya sebar, daya lekat, dan ph kedua sediaan salep yang dihasilkan mengalami fluktuatif sebelum dan setelah cycling test. sementara nilai viskositas kedua sediaan salep mengalami kenaikan viskositas setelah cycling test. hasil analisis uji keamanan sediaan salep menggunakan metode patch test memperlihatkan bahwa kedua sediaan salep negatif tidak adanya reaksi alergi terhadap kulit normal dari 15 sukarelawan yang diuji. kata kunci: ekstrak etanol residu heksan pliek u (eerhpu), salep, cycling test, staphylococcus aureus. the purpose of this study was to determine the activity of ethanol extract of pliek u hexane residue (eerhpu) from ointment formulation against stphylococcus aureus. the characterization results of showed that water, ash, water soluble extract and ethanol soluble extract of eerhpu contains were 17,27%, 15,33%, 60,98%, and 92,48% respectively. phytochemical screening test results showed that eerhpu were negative containing alkaloids, flavonoids, tannins, saponins, steroids, and triterpenoids. antibacterial activity test results showed that eerhpu at a concentration of 200 mg/ml have highest activity against s. aureus with diameter of inhibination zone was 11,4 mm. the antibacterial of activity of eerhpu ointment showed that fx ointment (200 mg/ml) and fy (400 mg/ml) exhibit antibacterial activity against s. aureus with the diameter of inhibition zone were 6,77 mm and 14,97 mm respectively. the evalutions of eerhpu ointment of fx and fy revealed that these two formulas have changes in organoleptic and homogenity after cycling test mean while the spread power, stickness and ph of these formulas have fluctuative values before and after cycling test. while the viscosity values of ointment increased after the cycling test. patch test methode results showed that both of formulas did not have an alergic reaction fowards the normal skin of the 15 voluenter tested. keywords: ethanol extract of pliek u hexane residue (eerhpu, ointment, cycling test, staphylococcus

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