Abstrak

Baca Juga : HUBUNGAN KADAR FERITIN DALAM DARAH DENGAN FUNGSI JANTUNG PADA PENDERITA THALASEMIA DI RUMAH SAKIT UMUM DAERAH DR. ZAINOEL ABIDIN RNBANDA ACEH (Tengku dinda mutiara, 2014) ,

Baca Juga : HUBUNGAN DENSITAS MINERAL TULANG DENGAN KADAR FERITIN SERUM PADA PASIEN THALASSEMIA MAYOR (dr. Rachmi, 2019) ,

cholesterol (hdl). hasil analisa feritin serum dengan kolesterol total didapatkan p=0,193 (p>0,05), dengan kolesterol hdl didapatkan p=0,85 (p>0,05), dengan kolesterol ldl didapatkan p=0,08 (p>0,05), dan dengan trigliserida didapatkan p=0,886 (p>0,05). kesimpulan yang didapatkan dari hasil tersebut yaitu tidak terdapat pengaruh kadar feritin serum terhadap perubahan fraksi lipid pada pasien thalasemia di rsudza banda aceh. kata kunci : feritin serum, fraksi lipid, transfusi darah, thalasemia abstract thalassemia is one of life-threatening hemoglobinopathy disease due to a decrease or failure to produce red blood cells. blood transfusion of thalassemia patients leads to accumulation of iron in the body and characterized by an increase of ferritin serum levels. the accumulation of iron caused the formation of free radicals that can damage internal organs and changes metabolism regulation such as lipid metabolism. this study aims to determine the correlation of ferritin serum on lipid fraction changes in thalassemia patients. the respondents of this study were 31 adult thalassemia patients obtained by using non-probability sampling technique. the data was analyzed using pearson correlation test for total cholesterol, low density lipoprotein (ldl-c), and triglyceride and spearman correlation test for high density lipoprotein (hdl-c). the statistical analysis showed that there was no correlation between ferritin serum and total cholesterol (p=0,193), hdl-c (p=0,85), ldl-c (0,08), and triglyceride (p=0,886). this study concluded that there was no correlation between ferritin serum level and lipid fraction changes in thalassemia patients in rsudza banda aceh. keywords: ferritin serum, lipid fraction, blood transfusion,

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