Abstrak

Baca Juga : PROPORSI MUAL DAN MUNTAH AKUT DAN TERTUNDA YANG DIINDUKSI KEMOTERAPI DENGAN REJIMEN TAXOTERE ADRIAMYCIN CYCLOPHOSPHAMIDE(TAC) PADA PENDERITA KANKER PAYUDARA DI RUANG MAMPLAM III BLUD RSUD DR. ZAINOEL ABIDIN BANDA ACEH (VIVI ROSANDI, 2016) ,

Baca Juga : GAMBARAN JUMLAH NEUTROFIL SEBELUM DAN SESUDAH KEMOTERAPI BERDASARKAN JENIS REGIMEN KEMOTERAPI PADA PASIEN KANKER DI RUMAH SAKIT UMUM DAERAH DR. ZAINOEL ABIDIN BANDA ACEH (M HABIBIE RUNANDA, 2019) ,

of the combination therapy of ondansetronedexamethasone to granisetrone – dexamethasone in the preventing of acute nausea - vomiting due to tac regimen of chemotherapy in breast cancer patients. patients and methods. this study is a clinical trial with single-blind and cross-over design , the first group received ondansetron 32mg and dexamethasone 20mg on the first cycle and then got granisetron 1mg and dexamethasone 20 mg on the second cycle or vice versa in the second group . this research was conducted at dr.zainoel abidin’s hospital from june to august 2013 . all subjects performed an assessment of the quality of nausea , vomiting frequency , therapeutic response and side effects within the first 24 hours of chemotherapy. results. there was no significant difference in the degree of nausea , vomiting and frequency response between combination therapy with ondansetrone – dexamethasone to granisetrone- dexamethasone in the prevention of acute nausea and vomiting due to tac regimen. the most common side effects reported were decreased appetite, headache, abdominal discomfort, insomnia and impaired vision. side effects more visual disturbances reported in ondansetron group, p = 0.02. conclusion. granisetron - dexamethasone combination therapy has the same effectiveness with ondansetron -dexamethasone , both well tolerated , although side effects were reported more visual impairment in the ondansetron group. keywords : antiemetics, breast cancer, chemotherapy, dexamethasone, graniisetrone, ondansetrone, tac

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GAMBARAN EFEK SAMPING KEMOTERAPI BERBASIS ANTRASIKLIN PADA PASIEN KANKER PAYUDARA DI RUMAH SAKIT UMUM DAERAH DR. ZAINOEL ABIDIN BANDA ACEH (SARAH NABILA, 2015) ,

PERBEDAAN KADAR NEUTROFIL PASIEN KANKER PAYUDARA SEBELUM DAN SESUDAH KEMOTERAPI DI BLUD RSUD DR. ZAINOEL ABIDIN BANDA ACEH (Ridha Mawaddah, 2015) ,

PERBANDINGAN KADAR ASAM URAT SEBELUM DAN SETELAH KEMOTERAPI SIKLUS I PADAPASIENKANKER PAYUDARA DANRNKANKER OVARIUMDI BLUDRNDR. ZAINOEL ABIDIN RNBANDA ACEH (Suci Rahmaniar, 2014) ,