Abstrak

Baca Juga : UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL RIMPANG KENCUR (KAEMPFERIA GALANGA L) TERHADAP ISOLAT KLINIS KLEBSIELLA PNEUMONIAE PENGHASIL ESBL SECARA IN VITRO (FITRA HAYATI, 2017) ,

Baca Juga : KONSENTRASI HAMBAT MINIMUM DAN BUNUH MINIMUM EKSTRAK ETANOL RIMPANG KENCUR (KAEMPFERIA GALANGA L.) TERHADAP PERTUMBUHAN CANDIDA ALBICANS (ATHIA FAHRANI, 2018) ,

n 50%. sementara itu, kelompok kontrol negatif adalah akuades steril. hasil dari penelitian menunjukkan bahwa ekstrak etanol rimpang kencur dengan konsentrasi 5%, 20%, 35%, dan 50% memberikan daya hambat terhadap pertumbuhan mrsa dengan rata-rata diameter zona hambat sebesar 11,17 mm, 12,47 mm, 13,38 mm, dan 14,21 mm. sedangkan kontrol negatif tidak menunjukkan adanya daya hambat. hasil analisis data menggunakan anova dan uji duncan (p < 0,05) menunjukkan bahwa ekstrak etanol rimpang kencur memiliki pengaruh yang nyata dalam menghambat pertumbuhan methicillin resistant staphylococcus aureus isolat klinis. kesimpulan dari penelitian ini adalah ekstrak etanol rimpang kencur memiliki daya hambat terhadap pertumbuhan methicillin resistant staphylococcus aureus isolat klinis dan semakin besar konsentrasi yang diberikan, maka semakin luas diameter zona hambat yang terbentuk. kata kunci : kaempferia galanga l., antibakteri, methicillin resistant staphylococcus aureus ? abstract increased rates of bacterial resistance to antibiotic is becoming a problem in the treatment of infection disease. mrsa is a strain of bacteria resistant to antibiotics and is frequent cause of infection in health care and comunity. herbs have secondary matabolite as a substance that can work as an antimicrobial agent. galanga was known to have antimicrobial and antifungal activity. this study aims to determine the antibacterial ability of inhibitory ethanolic extract of galanga rhizome (kaempferia galanga l.) against clinical isolates methicillin resistant staphylococcus aureus. this kind of study is true experimental laboratories used a completely randomized design (crd), which consist of 5 group of treatment and 5 repetitions. inhibition test was conducted using the disc diffusion assay method. the treatment consist of the ethanolic extract of galanga rhizome concentration of 5%, 20%, 35%, and 50%.meanwhile the negative control is sterile distilled water. the result of this study showed that the ethanolic extract of galanga rhizome concentration of 5%, 20%, 35%, and 50% had mrsa growth inhibition with an average zone diameter of 11,17 mm, 12,47 mm, 13,38 mm, and 14,21 mm. while the negative control did not show any inhibition zone. the result of data analysis with anova and duncan test (p < 0,05) showed that ethanolic extract of galanga rhizome has a significant effect on the growth of clinical isolates methicillin resistant staphylococcus aureus. the conclution of this study are ethanolic extract of galanga rhizome has an ability of inhibitory on the growth of clinical isolates methicillin resistant staphylococcus aureus and increased of the concentration also increased the inhibitory zone. keywords : kaempferia galanga l., antibacterial, methicillin resistant staphylococcus

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