Abstrak

Baca Juga : UJI AKTIVITAS ANTIJAMUR MINYAK ATSIRI KULIT BUAH JERUK NIPIS (CITRUS AURANTIFOLIA(CHRISTM.)SWINGLE) TERHADAP ISOLAT KLINIS CANDIDA ALBICANS SECARA IN VITRO (Wahyu Desriana Putri, 2014) ,

Baca Juga : PENENTUAN KONSENTRASI HAMBAT MINIMUM DAN KONSENTRASI BUNUH MINIMUM MINYAK ATSIRI KULIT JERUK NIPIS (CITRUS AURANTIFOLIA (CHRISTM.) SWINGLE) TERHADAP ISOLAT KLINIS CANDIDA ALBICANS (Fauzi Satria, 2015) ,

akuan dengan konsentrasi 10%, 20%, 30%, 40% dan 50% dan 1 kelompok kontrol negatif (akuades dan tween 80). uji aktivitas antijamur dilakukan dengan menggunakan metode difusi cakram kirby-bauer. hasil penelitian menunjukkan minyak atsiri dengan konsentrasi 10%, 20%, 30%, 40% dan 50% memiliki aktivitas antijamur terhadap isolat klinis candida albicans dengan diameter rata-rata zona hambat 9 mm, 10,62 mm, 11,75 mm, 11,62 mm dan 13,50 mm. hasil analisis data dengan anova dan dilanjutkan dengan uji duncan (?=0,05) menunjukkan bahwa berbagai konsentrasi minyak atsiri kulit buah jeruk nipis memiliki pengaruh yang nyata dalam menghambat pertumbuhan isolat klinis candida albicans secara in vitro. konsentrasi minyak atsiri 50% menunjukkan aktivitas antijamur yang paling optimal. kata kunci: minyak atsiri, citrus aurantifolia (christm.) swingle, candida albicans. ? abstract candida albicans is one of the normal flora in a healthy person which can be pathogenic. the resistance of azole as drug of choice for candida albicans has been demonstrated, therefore nowadays the use of traditional medicine is encouragingly developed. one of emperically proved traditional medicine is lime (citrus aurantifolia (christm.) swingle) that has been known for its antimicrobial effects. essential oil are a large group of volatile vegetable oils and provide a distinctive scent that can be used as a drug in many dosage form. the purpose of this study was to determine the antifungal activity of the essential oil of lime peel (citrus aurantifolia (christm.) swingle ) against clinical isolates of candida albicans. this study used a completely randomized design (crd) with 4 repetitions that consisted of 5 treatment groups with a concentration of 10 % , 20 % , 30 % , 40 % and 50 % and negative control group (distilled water and tween 80). antifungal activity test conducted using kirby-bauer disc diffusion method. the result showed the essential oil with a concentration of 10 % , 20 % , 30 % , 40 % and 50 % have antifungal activity against clinical isolates of candida albicans with an average diameter of inhibition zone 9 mm, 10,62 mm , 11,75 mm , 11,62 mm and 13.50 mm respectively. the results of this study were analyzed by anova followed by duncan test (?=0,05)showed that different concentrations of essential oil of lemon rind has a significant effect against clinical isolates of candida albicans in vitro. essential oil in 50% concentration showed the most optimal antifungal activity. keywords: essential oil, citrus aurantifolia (christm.)swingle, candida

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