Abstrak

Baca Juga : ANALISIS MIKROSKOPIK JUMLAH MAKROFAG TIKUS DENGAN PERIODONTITIS KRONIS SETELAH PEMBERIAN JAHE MERAH (ZINGIBER OFFICINALE VAR. RUBRA) (Melati Hayatul Husni, 2016) ,

Baca Juga : KONSENTRASI HAMBAT MINIMUM (KHM)DAN KONSENTRASI BUNUH MINIMUM (KBM) EKSTRAK JAHE MERAH (ZINGIBER OFFICINALE VAR. RUBRUM) TERHADAP PORPHYROMONAS GINGIVALIS (Zuraida, 2015) ,

kronis pada tikus dilakukan dengan mengaplikasikan wire 0,008 inci pada tepi gingiva gigi insisivus rahang bawah, kemudian diberikan ekstrak jahe merah (zingiber officinale var rubrum) yang memiliki senyawa aktif dan memiliki pengaruh terhadap respon inflamasi. hasil dari penelitian ini menunjukkan bahwa pada preparat histopatologi dari jaringan periodontal tikus tidak ditemukan adanya neutrofil, sehingga dapat disimpulkan bahwa ekstrak jahe merah (zingiber officinale var rubrum) tidak berpengaruh terhadap kuantitas neutrofil. kata kunci: inflamasi, jaringan periodontal, p. gingivalis, gingerol. abstract name : hessyi amanda pratiwi study program : dentistry faculty : dentistry title : the quantity of neutrophils due to the application of red ginger (zingiber officinale var rubrum) extract of chronic periodontitis in rats (rattus norvegicus) chronic periodontitis is the most common form of periodontitis. the major etiology of periodontitis is gram-negative anaerobic bacteria, such as aggregatibacter actinomycetemcomitans, treponema denticola, tannarela forsythia and porphyromonas gingivalis which locally invade periodontal tissues and cause deregulation of neutrophils as innate immune. neutrophils are characteristic of acute inflammation and also be found in the chronic inflammation. the aim of study was to evaluate the quantity of neutrophils due to the application of red ginger (zingiber officinale var rubrum) extract of rat chronic periodontitis. in order to induce experimental periodontitis, the mandibular insisivus was assigned to receive wire 0,008 inch in marginal gingival. then, red ginger (zingiber officinale var rubrum) extract that has bioactive compounds was topically administered to the rats. the result of this study showed there were no neutrophils in histopathologic of rat’s periodontal tissues. it concluded that there was no effect of red ginger (zingiber officinale var rubrum) extract toward the quantity of neutrophils. keywords: inflammation, periodontal tissues, p. gingivalis,

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